Synopsis of resource:
Well presented video with links to the authors publication, discussing the early social and motor signs of Autism which emerge between 6 and 12 months of age, and may be associated with the dissolution of transient social-brain structures, namely the cortical subplate in the fronto-temporal-parietal areas and the external granular layer of the cerebellum.
For people interested in a theory of the pathophysiology of emergence of early signs of autism.
Key learning outcomes
- The early social and motor signs of autism spectrum disorder emerge between the ages of 6 and 12months.
- Altered dissolution of transient brain structures in the fronto-temporo-parietal cortex and cerebellum may underlie the emergence of these early signs.

Author
Mijna Hadders-Algra MD, PhD is emeritus professor of Developmental Neurology in Groningen, the Netherlands. Her research deals in particular with pathophysiology of neurodevelopmental disorders, early detection of neurodevelopmental disabilities and early intervention. The research on pathophysiology focuses on general movements and postural control, that on early detection on the general movements, the Infant Motor Profile and Standardized Infant NeuroDevelopmental Assessment. Together with Tineke Dirks and Schirin Akhbari Ziegler she developed the family-centered early intervention program COPCA (COPing with and CAring for infants with special needs).
She (co)authored >300 publications in peer reviewed journals, and she authored/edited eight books, including a book on Early Detection and Early Intervention in Developmental Motor Disorders. She frequently teaches and lectures about early detection and early intervention worldwide.
